Ipamorelin

A$79.00

Ipamorelin, a selective growth hormone secretagogue studied in pituitary models.

Research use only. Not for human or veterinary use.

In stock

All prices are in AUD. Ships from Australia with tracked express shipping, $15 flat, 1 to 2 business days, free on orders over $200. Research use only, not for human or veterinary use.

  • Testing status on this page
  • Same-day dispatch before 2pm
  • Dispatched from Australia
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Research use only

Not for human or veterinary use.

Laboratory chemical

Supplied for in vitro research. We publish specifications and handling guidance only, with no protocols and no advice on use.

Not on the ARTG

Absent from the Australian Register of Therapeutic Goods and never evaluated by the TGA for safety, quality or efficacy. Absence from the register is not an approval and does not authorise any other use.

Who can order

You must be 18 or over and purchasing solely for lawful research.

What is Ipamorelin?

Ipamorelin is a selective pentapeptide agonist at the ghrelin GHS-R1a receptor. It is used in pituitary somatotroph culture and studied for its receptor selectivity, with minimal cross-activity at ACTH and prolactin endpoints. NuVion stocks it in Australia as a 10mg lyophilised vial.

  • Selective pentapeptide agonist at the ghrelin GHS-R1a receptor
  • Used in pituitary somatotroph culture models
  • Applied in receptor selectivity and second messenger assays
  • Supplied lyophilised, purity by RP-HPLC and identity by mass spectrometry

Ipamorelin structure and research use

Ipamorelin has the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2. It belongs to the growth hormone releasing peptide family, synthetic agonists of the ghrelin receptor GHS-R1a, alongside GHRP-2 and GHRP-6. What sets it apart in the literature is selectivity: in somatotroph work it shows minimal cross-activity at ACTH and prolactin endpoints.

Ipamorelin research applications

  • Competition binding at recombinant GHS-R1a in membrane preparations, run against labelled ghrelin or small-molecule tracers
  • Calcium mobilisation in HEK293 or CHO lines stably expressing GHS-R1a, read with fluorescent calcium indicators
  • IP-One accumulation assays measuring Gq pathway output, paired with transcriptional reporter readouts of that branch
  • Beta-arrestin recruitment and receptor internalisation measured by BRET, enzyme complementation or imaging formats

Ipamorelin key facts

Type Synthetic pentapeptide, GHS-R1a agonist
Amino acid count 5
Also known as NNC 26-0161, ipamorelin acetate (salt form)
Vial size 10mg, lyophilised
Purity 99.71% by RP-HPLC, Janoshik Analytical
Analysed 9 July 2026

Independent test: a sample of this product was analysed by Janoshik Analytical on 9 July 2026, purity 99.71% by RP-HPLC, test number 195040. The full report opens from the lab band on this page.

Why buy Ipamorelin from NuVion

Testing status on every page

Published results show the measured purity, the date and the certificate.

Australian stock, domestic post

Held in Australia and sent tracked in plain outer packaging.

Specifications

CAS Number 170851-70-4
Molecular Weight 711.9
Molecular Formula C38H49N9O5

Storing and handling Ipamorelin

Before reconstitution
Keep the sealed vial cool, dry and out of direct light. General practice for lyophilised peptides.
After reconstitution
Reconstitute with bacteriostatic or sterile water, store at 2 to 8°C and avoid repeated freeze-thaw cycles. No stability-tested shelf life is published for this product.

Reconstitution and storage Volumes, concentrations and storage at a glance.

Ipamorelin questions

Where can I buy ipamorelin in Australia?
NuVion stocks ipamorelin in Australia as a 10mg vial of lyophilised powder, posted from Australian stock on a tracked express service. A sample was analysed by Janoshik Analytical on 9 July 2026, with purity of 99.71% by RP-HPLC. It also comes in the Metabolic Signalling Set, the Somatotropic Axis Set, the Metabolic Signalling Set (Extended) and the GHRH & Secretagogue Pair. Bacteriostatic water is sold separately. ipamorelin is supplied as a research material only and is not on the Australian Register of Therapeutic Goods.
What is Ipamorelin used for in research?
It is used as a selective agonist at the ghrelin receptor GHS-R1a in binding, calcium mobilisation, IP-One and arrestin recruitment assays. Its selectivity makes it useful when a GHS-R1a signal has to be separated from other receptor systems present in the same cells.
How does Ipamorelin work at the cell level?
GHS-R1a is a class A G protein-coupled receptor encoded by GHSR, expressed in pituitary somatotroph cells and in defined hypothalamic and peripheral neuronal populations. The receptor is notable for high constitutive activity, signalling at around half its maximal level with no ligand bound, which makes it a standard system for studying inverse agonism as well as agonism. The Ipamorelin research profile covers the mechanism in full.
Why does Ipamorelin begin with an Aib residue?
Aib, alpha-aminoisobutyric acid, restrains the N terminus of Ipamorelin. It is a quaternary residue with two methyl groups on the alpha carbon, so it favours helical and turn geometry, has no alpha proton and resists aminopeptidase attack.
Does Ipamorelin share any sequence with ghrelin?
No. The Ipamorelin sequence has nothing in common with ghrelin, the endogenous GHS-R1a ligand, and it lacks the Ser3 octanoyl group that ghrelin requires. It is a peptidomimetic that reaches the same binding site by a different chemistry.
What mass does identity testing report for Ipamorelin?
Identity work reports the mass of the free peptide, which is 711.9 g/mol for the formula C38H49N9O5. Ipamorelin is usually supplied as the acetate salt, so the free peptide mass is the figure that appears in mass spectrometry.
Is ipamorelin a GHRP?
Yes. It is a growth hormone releasing peptide, a synthetic agonist of the ghrelin receptor GHS-R1a, in the same family as GHRP-2 and GHRP-6.
How is ipamorelin different from CJC-1295?
They act at different receptors. Ipamorelin is an agonist at the ghrelin receptor GHS-R1a. CJC-1295 No DAC is a GHRH analogue and acts at the GHRH receptor. NuVion stocks both separately, and together in the CJC-1295 No DAC / Ipamorelin Blend.

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