Growth Hormones

The growth hormones category collects the peptides and proteins used to study GHRH receptor and GHS-R1a signalling, JAK2-STAT5 activation and IGF-1 receptor pharmacology in pituitary and other cell culture models. HGH is recombinant human growth hormone, a 191-residue protein that dimerises the GH receptor and activates JAK2-STAT5, and IGF-1 LR3 is an extended analogue of IGF-1 with reduced affinity for IGF binding proteins, used in IGF-1 receptor phosphorylation and PI3K-Akt assays. Sermorelin (GHRH 1-29) and CJC-1295 No DAC (a four-substitution GRF 1-29 analogue) are GHRH receptor agonists read out by cAMP accumulation. Ipamorelin, GHRP-2 and GHRP-6 are synthetic GHS-R1a agonists used in calcium mobilisation, inositol phosphate and GH release assays in somatotroph cell lines, and they differ in their selectivity over ACTH and prolactin release.
Tesamorelin, a further GHRH analogue, is listed under the metabolism category. Compounds in this category are independently tested by Janoshik Analytical for RP-HPLC purity and mass spectrometry identity, with the Certificate of Analysis for tested batches published on the product page. Supplied as laboratory chemicals for in vitro research use only, dispatched from within Australia.

Structure, mechanism, handling and analysis notes for these compounds are in the NuVion peptide research library: CJC-1295, Ipamorelin, GHRP-2, GHRP-6, HGH, IGF-1 LR3, IGF-1 DES, MK-677, Sermorelin, MGF and PEG-MGF, AOD-9604, ACE-031 and Follistatin.