CJC-1295 No DAC / Ipamorelin is a two-peptide blend of a GHRH analogue and a ghrelin receptor agonist supplied in a single vial. It is used in pituitary somatotroph culture where the two receptor pathways that drive growth hormone release are studied side by side, and NuVion stocks it in Australia as a 10mg lyophilised vial holding 5mg of each peptide.
- 5mg CJC-1295 No DAC and 5mg Ipamorelin in one vial
- Pairs a GHRH receptor agonist with a ghrelin receptor (GHS-R1a) agonist
- Used in pituitary somatotroph culture models
- CJC-1295 No DAC and Ipamorelin each independently tested by Janoshik for purity
CJC-1295 No DAC / Ipamorelin blend components
The blend holds two distinct molecules in one vial. CJC-1295 No DAC, also sold as Mod GRF 1-29, is a 29 amino acid GHRH analogue that acts at the GHRH receptor and signals through cyclic AMP. Ipamorelin is a pentapeptide agonist at the ghrelin receptor GHS-R1a, which signals through Gq and intracellular calcium. The two act at different receptors on the same pituitary cells, which is why they are compared and combined in somatotroph work. Each is also stocked on its own as a 10mg vial.
CJC-1295 No DAC / Ipamorelin research applications
- Growth hormone release from cultured pituitary somatotrophs measured by ELISA, with the blend run against each single component
- cAMP accumulation for the GHRH receptor arm read beside calcium mobilisation for the GHS-R1a arm in the same cell population
- Cell lines co-expressing both receptors, used to study crosstalk between Gs and Gq signalling
- Somatotroph readouts of CREB phosphorylation by western blot alongside growth hormone in the medium
CJC-1295 No DAC / Ipamorelin key facts
| Type | Synthetic peptide blend, two components |
|---|---|
| Components | CJC-1295 No DAC (GHRH (1-29) analogue, 29 residues), Ipamorelin (pentapeptide GHS-R1a agonist) |
| Component sequences | CJC-1295 No DAC: GRF(1-29) carrying D-Ala2, Gln8, Ala15 and Leu27; Ipamorelin: Aib-His-D-2-Nal-D-Phe-Lys-NH2 |
| Molecular mass | CJC-1295 No DAC near 3368 g/mol; Ipamorelin 711.9 g/mol |
| Also known as | CJC/Ipa blend, Mod GRF 1-29 and Ipamorelin blend |
| Vial size | 10mg, lyophilised (5mg CJC-1295 No DAC, 5mg Ipamorelin) |
Research profiles: CJC-1295: structure, mechanism and research use and Ipamorelin: structure, mechanism and research use
Independent testing: the two compounds in this blend are each tested on their own by Janoshik Analytical for purity by RP-HPLC. CJC-1295 No DAC 99.46% (test 195039) and Ipamorelin 99.71% (test 195040). The certificates are linked in the lab band on this page.
