GHRP-2 is a synthetic hexapeptide active at the ghrelin and growth hormone secretagogue receptor family. It is used in pituitary cell models to characterise receptor pharmacology through calcium flux and second messenger assays, and NuVion stocks it in Australia as a 10mg lyophilised vial.
- Synthetic hexapeptide active at the ghrelin and GHS receptor family
- Used to characterise receptor pharmacology in pituitary cell models
- Applied in calcium flux and second messenger assays
- Supplied lyophilised, purity by RP-HPLC and identity by mass spectrometry
GHRP-2 structure and research use
GHRP-2, also known as pralmorelin, has the sequence D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2. It is one of the growth hormone releasing peptides, synthetic agonists of the ghrelin receptor GHS-R1a, alongside GHRP-6 and ipamorelin. In the laboratory it serves as a reference compound for secretagogue receptor pharmacology in pituitary cell models.
GHRP-2 research applications
- Competition binding on GHS-R1a membrane preparations or whole cells, ranking affinity against ghrelin, GHRP-6 and hexarelin
- IP-One HTRF inositol phosphate accumulation and PKC translocation assays that quantify the Gq arm
- Primary pituitary cell culture, with GH released into the medium quantified by ELISA
- LC-MS/MS and RP-HPLC method development, where the naphthylalanine residue gives a distinctive fragmentation pattern
GHRP-2 key facts
| Type | Synthetic peptide, growth hormone secretagogue, GHS-R1a agonist |
|---|---|
| Amino acid count | 6 residues, C-terminal amide |
| Sequence | D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 |
| Also known as | Pralmorelin, KP-102, GHRP-2, growth hormone releasing peptide 2 |
| Vial size | 10mg, lyophilised |
| Purity | 99.22% by RP-HPLC, Janoshik Analytical |
| Analysed | 23 April 2026 |
Research profile: GHRP-2: structure, mechanism and research use
Independent test: a sample of this product was analysed by Janoshik Analytical on 23 April 2026, purity 99.22% by RP-HPLC. The certificate is shown in the lab band on this page.







