Pinealon is a synthetic tripeptide bioregulator (Glu-Asp-Arg) from the Khavinson short peptide series. It is used in neuronal and cortical cell culture to study oxidative stress, cell viability and gene regulation, and NuVion stocks it in Australia as a 20mg lyophilised vial.
- Synthetic tripeptide bioregulator (Glu-Asp-Arg)
- Used in neuronal and cortical cell culture models
- Applied in oxidative stress and cell viability assays
- Supplied lyophilised, purity by RP-HPLC and identity by mass spectrometry
Pinealon structure and research use
Pinealon is three amino acids long: glutamic acid, aspartic acid and arginine, written EDR in one-letter code. It belongs to the Khavinson series of short synthetic peptides, alongside the tetrapeptide Epithalon. In the laboratory it is used in neuronal and cortical cell models for work on oxidative stress, cell viability and gene regulation.
Pinealon research applications
- Reactive oxygen species assays with DCFH-DA or MitoSOX in PC12 cells, SH-SY5Y cells and primary neuronal cultures
- Phospho-ERK1/2 Western blotting and cell cycle analysis by DNA content, in time-course and concentration-response designs
- qPCR and immunocytochemistry for nestin, GAP43, beta-tubulin III and doublecortin in neural progenitor and neuronal cell lines
- Peptide-DNA interaction studies by electrophoretic mobility shift, circular dichroism and isothermal titration calorimetry with defined oligonucleotides
Pinealon key facts
| Type | Synthetic linear tripeptide, short regulatory peptide |
|---|---|
| Amino acid count | 3 |
| Sequence | H-Glu-Asp-Arg-OH (EDR) |
| Also known as | EDR peptide, L-glutamyl-L-aspartyl-L-arginine, Glu-Asp-Arg |
| Vial size | 20mg, lyophilised |
| Purity | 99.39% by RP-HPLC, Janoshik Analytical |
| Analysed | 23 April 2026 |
Research profile: Pinealon: structure, mechanism and research use
Independent test: a sample of this product was analysed by Janoshik Analytical on 23 April 2026, purity 99.39% by RP-HPLC. The certificate is shown in the lab band on this page.
