BPC-157 / TB-500 is a two-peptide blend supplied in a single vial. It is used in fibroblast, endothelial and epithelial culture where cell migration, adhesion and actin dynamics are examined together, and NuVion stocks it in Australia as a 10mg lyophilised vial holding 5mg of each peptide.
- 5mg BPC-157 and 5mg TB-500 in one vial
- Used in fibroblast, endothelial and epithelial culture models
- Applied in cell migration, adhesion and actin dynamics assays
- BPC-157 and TB-500 each independently tested by Janoshik for purity
BPC-157 / TB-500 blend components
The blend holds two distinct molecules in one vial. BPC-157 is a synthetic 15 amino acid peptide modelled on a gastric protein sequence, studied at focal adhesion and VEGFR2 signalling. TB-500 is a seven residue fragment of thymosin beta-4 carrying the Leu-Lys-Lys-Thr-Glu-Thr motif through which the parent protein binds actin. Each is also stocked on its own as a 10mg vial.
The same two peptides also appear in GLOW, which adds GHK-Cu, and in KLOW, which adds GHK-Cu and KPV.
BPC-157 / TB-500 research applications
- Scratch and transwell migration in fibroblast, endothelial or epithelial cultures, with the blend run against each single component
- FAK and paxillin phosphorylation by western blot, the adhesion signalling readout tied to BPC-157
- G-actin to F-actin ratio with phalloidin staining, the actin readout tied to TB-500
- Endothelial tube formation on basement membrane matrix, run with VEGFR2 knockdown or kinase inhibitor controls
BPC-157 / TB-500 key facts
| Type | Synthetic peptide blend, two components |
|---|---|
| Components | BPC-157 (15 residues), TB-500 (thymosin beta-4 fragment, 7 residues) |
| Component sequences | BPC-157: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val; TB-500: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln |
| Molecular mass | BPC-157 1419.5 g/mol; TB-500 889 g/mol |
| Also known as | BPC/TB blend, BPC-157 and TB-500 blend |
| Vial size | 10mg, lyophilised (5mg BPC-157, 5mg TB-500) |
Research profiles: BPC-157: structure, mechanism and research use and TB-500: structure, mechanism and research use
Independent testing: the two compounds in this blend are each tested on their own by Janoshik Analytical for purity by RP-HPLC. BPC-157 99.93% (test 234332) and TB-500 99.91% (test 195037). The certificates are linked in the lab band on this page.
