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NuVion Cagrilintide research peptide vial

Cagrilintide

A$149.00

Cagrilintide, a long-acting amylin analogue studied in metabolic research.

Research use only. Not for human or veterinary use.

In stock

All prices are in AUD. Ships from Australia with tracked express shipping, $15 flat, 1 to 2 business days, free on orders over $200. Research use only, not for human or veterinary use.

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  • Dispatched from Australia
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Research use only

Not for human or veterinary use.

Laboratory chemical

Supplied for in vitro research. We publish specifications and handling guidance only, with no protocols and no advice on use.

Not on the ARTG

Absent from the Australian Register of Therapeutic Goods and never evaluated by the TGA for safety, quality or efficacy. Absence from the register is not an approval and does not authorise any other use.

Who can order

You must be 18 or over and purchasing solely for lawful research.

What is Cagrilintide?

Cagrilintide is a long-acting synthetic analogue of human amylin, active at the AMY1R, AMY3R and calcitonin receptors. It is used as a reference compound in amylin and calcitonin receptor pharmacology in vitro, and NuVion stocks it in Australia as a 10mg lyophilised vial.

  • Long-acting synthetic analogue of human amylin
  • Agonist at AMY1R, AMY3R and calcitonin receptors
  • Used in receptor binding and second messenger assays
  • Supplied lyophilised, purity by RP-HPLC and identity by mass spectrometry

Cagrilintide structure and research use

Cagrilintide is built on the 37 amino acid sequence of human amylin, with amino acid substitutions and a fatty acid side chain added to make it stable in solution and long acting. It is an agonist at the amylin receptors AMY1R and AMY3R and at the calcitonin receptor. In the laboratory it is used as a reference compound in receptor binding and second messenger assays.

Cagrilintide research applications

  • Cyclic AMP accumulation in cells co-expressing the calcitonin receptor with a defined RAMP
  • Competition binding at AMY1R, AMY2R, AMY3R and the calcitonin receptor to rank subtype affinity
  • Thioflavin T fluorescence assays comparing fibril formation with that of native human amylin
  • Albumin binding and free fraction measured by equilibrium dialysis or ultrafiltration in serum-containing medium

Cagrilintide key facts

Type Synthetic acylated amylin analogue
Amino acid count 37
Parent peptide Human amylin (IAPP)
Modification C20 fatty diacid side chain via a linker
Structural feature N-terminal disulfide loop, amidated C-terminus
Receptors AMY1R, AMY2R, AMY3R and the calcitonin receptor
Vial size 10mg, lyophilised
Purity 99.94% by RP-HPLC, Janoshik Analytical
Analysed 5 February 2026

See how Cagrilintide compares in Retatrutide vs Tirzepatide vs Cagrilintide.

Research profile: Cagrilintide: structure, mechanism and research use

Independent test: a sample of this product was analysed by Janoshik Analytical on 5 February 2026, purity 99.94% by RP-HPLC. The certificate is shown in the lab band on this page.

Why buy Cagrilintide from NuVion

Testing status on every page

Published results show the measured purity, the date and the certificate.

Australian stock, domestic post

Held in Australia and sent tracked in plain outer packaging.

Specifications

Chemical structure of Cagrilintide Janoshik test report, Cagrilintide, purity 99.939%
CAS Number 1415456-99-3
Molecular Weight 4409
Molecular Formula C194H312N54O59S2

Storing and handling Cagrilintide

Before reconstitution
Keep the sealed vial cool, dry and out of direct light. General practice for lyophilised peptides.
After reconstitution
Reconstitute with bacteriostatic or sterile water, store at 2 to 8°C and avoid repeated freeze-thaw cycles. No stability-tested shelf life is published for this product.

Reconstitution and storage Volumes, concentrations and storage at a glance.

Cagrilintide questions

Where can I buy cagrilintide in Australia?
NuVion stocks cagrilintide in Australia as a 10mg vial. Add it to your cart on this page and the order is posted from Australian stock on a tracked express service. This product is supplied as a research material only and is not on the Australian Register of Therapeutic Goods.
What is Cagrilintide used for in research?
It is used as a reference agonist at the amylin receptor complexes and the calcitonin receptor in cyclic AMP accumulation and competition binding assays, in RAMP dependence experiments, in arrestin recruitment work, and in aggregation studies comparing it with native human amylin.
How does Cagrilintide work at the cell level?
The amylin receptors are not separate gene products. Each is a complex formed when the calcitonin receptor associates with one of the receptor activity-modifying proteins: RAMP1 gives AMY1R, RAMP2 gives AMY2R and RAMP3 gives AMY3R. The RAMP changes the ligand binding pocket of the calcitonin receptor so that amylin is preferred over calcitonin, which means expressing the calcitonin receptor alone produces a different pharmacology from co-expressing it with a RAMP. The Cagrilintide research profile covers the mechanism in full.
How does Cagrilintide differ from native human amylin?
Cagrilintide replaces residues in the aggregation-prone middle region of human amylin with those found in salmon calcitonin and rodent amylin. The result stays monomeric in solution far longer than the parent, and it also carries a C20 diacid side chain.
Does Cagrilintide keep the disulfide loop of amylin?
Yes. Cagrilintide retains the N-terminal disulfide loop and the amidated C-terminus of human amylin, since receptor activation depends on both. The disulfide bond is confirmed in mass spectrometry by comparing reduced and non-reduced samples.
Why do Cagrilintide solutions foam easily?
The acyl chain gives Cagrilintide a surfactant-like character. Solutions foam readily, the peptide gathers at air-liquid interfaces, and it dissolves more slowly than an unmodified peptide of the same length. In serum-containing medium the same chain associates with albumin.
Is cagrilintide a GLP-1?
No. Cagrilintide is an amylin analogue and acts at the amylin and calcitonin receptors. GLP-1 receptor agonists are a separate class. NuVion also stocks tirzepatide (GLP-1 and GIP) and retatrutide (GLP-1, GIP and glucagon).
What form does cagrilintide arrive in?
As a lyophilised (freeze-dried) powder in a sealed vial. Bacteriostatic water is sold separately.

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