Tesamorelin is a synthetic 44 amino acid analogue of growth hormone releasing hormone, GHRH (1-44). It binds GHRH receptors on pituitary somatotrophs and is used as a reference compound in cAMP accumulation and PKA signalling assays. NuVion stocks it in Australia in 10mg and 20mg vials.
- Synthetic 44 amino acid GHRH (1-44) analogue
- Binds GHRH receptors on pituitary somatotrophs
- Used in cAMP accumulation and PKA signalling assays
- Supplied lyophilised, purity by RP-HPLC and identity by mass spectrometry
Tesamorelin structure and research use
Tesamorelin keeps the full 44 amino acid sequence of human GHRH and adds a trans-3-hexenoic acid group to the N-terminal tyrosine, a modification that slows enzymatic cleavage at that end of the chain. It acts at the GHRH receptor, a class B G protein-coupled receptor that signals through Gs, cyclic AMP and protein kinase A. In the laboratory it serves as a reference agonist in somatotroph culture and somatotropic axis research.
Tesamorelin vial sizes and prices, 10mg and 20mg
NuVion stocks tesamorelin in 10mg and 20mg vials. Both hold the same lyophilised peptide, and the 20mg vial works out cheaper per milligram.
| Vial size | Price | Price per mg | Availability |
|---|---|---|---|
| Tesamorelin 10mg | A$119.00 | A$11.90/mg | In stock |
| Tesamorelin 20mg | A$199.00 | A$9.95/mg | In stock |
Tesamorelin research applications
- Cyclic AMP accumulation by HTRF, AlphaScreen or reporter in cell lines expressing the GHRH receptor
- Western blot and qPCR measurement of CREB phosphorylation and Pit-1 expression downstream of the receptor
- Dipeptidyl peptidase 4 stability assays comparing the hexenoyl-modified peptide with unmodified GHRH (1-44)
- Growth hormone secretion from pituitary somatotroph culture, quantified in conditioned medium by ELISA
Tesamorelin key facts
| Type | Synthetic GHRH analogue |
|---|---|
| Amino acid count | 44 |
| Parent sequence | Human GHRH (1-44) amide |
| Modification | Trans-3-hexenoyl group at the N-terminal tyrosine |
| Purity | 99.68% by RP-HPLC, Janoshik Analytical |
| Analysed | 23 April 2026 |
Research profile: Tesamorelin: structure, mechanism and research use
Independent test: a sample of this product was analysed by Janoshik Analytical on 23 April 2026, purity 99.68% by RP-HPLC. The certificate is shown in the lab band on this page.







