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NuVion Glutathione 600mg lyophilised research vial

Glutathione

Price range: A$49.00 through A$89.00

Glutathione, the gamma-glutamyl tripeptide and principal cellular thiol, studied in redox balance and oxidative stress research.

Research use only. Not for human or veterinary use.

All prices are in AUD. Ships from Australia with tracked express shipping, $15 flat, 1 to 2 business days, free on orders over $200. Research use only, not for human or veterinary use.

  • Testing status on this page
  • Same-day dispatch before 2pm
  • Dispatched from Australia
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Research use only

Not for human or veterinary use.

Laboratory chemical

Supplied for in vitro research. We publish specifications and handling guidance only, with no protocols and no advice on use.

Not on the ARTG

Absent from the Australian Register of Therapeutic Goods and never evaluated by the TGA for safety, quality or efficacy. Absence from the register is not an approval and does not authorise any other use.

Who can order

You must be 18 or over and purchasing solely for lawful research.

What is Glutathione?

Glutathione is a tripeptide of glutamate, cysteine and glycine and the most abundant low molecular weight thiol in most cells. It is used in cell culture and enzyme assays to study redox balance, peroxide handling and conjugation chemistry, and NuVion stocks it in Australia as a 600mg or 1500mg lyophilised vial.

  • Reduced glutathione (GSH), gamma-L-glutamyl-L-cysteinyl-glycine
  • The principal cellular thiol, whose GSH to GSSG ratio reports redox state
  • Applied in redox ratio, glutathione S-transferase and S-glutathionylation assays
  • Supplied lyophilised in 600mg and 1500mg vials

Glutathione structure and research use

Glutamate joins cysteine through its side chain gamma carboxyl, a linkage aminopeptidases cannot cleave, so the tripeptide is broken down only by gamma-glutamyl transpeptidase at the cell surface. Almost all of its chemistry runs through the free sulfhydryl on the central cysteine. Two reduced molecules oxidise to one disulfide-linked dimer, GSSG, and the ratio between the two forms, held above 100 to 1 in healthy cytosol, is the standard laboratory reporter of oxidative stress. In the laboratory it is used in cell culture and enzyme models for work on peroxide handling, electrophile conjugation and redox signalling.

Glutathione vial sizes and prices, 600mg and 1500mg

NuVion stocks glutathione in 600mg and 1500mg vials. Both hold the same lyophilised peptide, and the 1500mg vial works out cheaper per milligram.

Glutathione vial sizes and prices in AUD
Vial sizePricePrice per mgAvailability
Glutathione 600mgA$49.00A$0.08/mgIn stock
Glutathione 1500mgA$89.00A$0.06/mgIn stock

Glutathione research applications

  • GSH to GSSG ratio quantification by enzymatic recycling assay or LC-MS, with the free thiol derivatised at the moment of collection
  • Glutathione peroxidase and glutathione reductase coupled assays following NADPH consumption at 340 nm
  • Glutathione S-transferase activity assays with model electrophile substrates such as CDNB
  • Protein S-glutathionylation mapping by redox proteomics with thiol blocking and selective reduction
  • Reference standard and calibration curves for thiol quantification by HPLC with monobromobimane or Ellman’s reagent

Glutathione key facts

Type Gamma-glutamyl tripeptide, the principal cellular thiol
Sequence gamma-L-glutamyl-L-cysteinyl-glycine
Molecular formula C10H17N3O6S
Molecular weight 307.32 g/mol (reduced form)
CAS number 70-18-8
Oxidised form GSSG, a disulfide-linked dimer of 612.6 g/mol
Also known as GSH, L-glutathione reduced, gamma-Glu-Cys-Gly
Vial sizes 600mg or 1500mg, lyophilised

Glutathione sits in NuVion’s Cellular Ageing range alongside NAD+, the cofactor pool behind the NADPH that regenerates reduced glutathione, and SS-31, the mitochondrial peptide studied on electron transport, with each compound in its own vial.

Research profile: Glutathione: structure, mechanism and research use

Why buy Glutathione from NuVion

Testing status on every page

Published results show the measured purity, the date and the certificate.

Australian stock, domestic post

Held in Australia and sent tracked in plain outer packaging.

Specifications

Storing and handling Glutathione

Before reconstitution
Keep the sealed vial cool, dry and out of direct light. General practice for lyophilised peptides.
After reconstitution
Reconstitute with bacteriostatic or sterile water, store at 2 to 8°C and avoid repeated freeze-thaw cycles. No stability-tested shelf life is published for this product.

Reconstitution and storage Volumes, concentrations and storage at a glance.

Glutathione questions

Where can I buy glutathione in Australia?
NuVion stocks glutathione in Australia in 600mg and 1500mg vials. Add it to your cart on this page and the order is posted from Australian stock on a tracked express service. Bacteriostatic water is sold separately. Glutathione is supplied as a research material only and is not on the Australian Register of Therapeutic Goods.
What is glutathione used for in research?
It is used to measure and manipulate redox state in cell culture, as the substrate in glutathione peroxidase, reductase and S-transferase assays, and as a reference standard for thiol quantification. Redox proteomics work also uses it to study S-glutathionylation, the reversible modification of cysteine residues on signalling proteins.
How does glutathione work at the cell level?
Glutathione peroxidases use two GSH molecules to reduce hydrogen peroxide and organic hydroperoxides, producing GSSG, and glutathione reductase regenerates GSH using NADPH from the pentose phosphate pathway. Glutathione S-transferases conjugate it to electrophiles for export, and glutaredoxins use it to reverse protein S-glutathionylation. The glutathione research profile covers the mechanism in full.
What is the difference between GSH and GSSG?
GSH is the reduced tripeptide with a free sulfhydryl, molecular weight 307.32. GSSG is two of those molecules joined through a disulfide, molecular weight 612.6. Healthy cytosol holds a ratio above 100 to 1 in favour of GSH, and a shift in that ratio is the standard reporter of oxidative stress. This product is the reduced form.
Which vial size should I choose?
Both vials hold the same lyophilised glutathione. The 600mg vial suits smaller runs. The 1500mg vial costs less per milligram and suits higher-volume work where the reconstituted stock is divided into single-use aliquots straight away.
Why does a glutathione solution lose activity on the bench?
The free thiol oxidises in air, faster at neutral or alkaline pH and faster again with trace copper or iron present, so a solution left uncovered becomes a GSH and GSSG mixture within hours. Fresh preparation, acidic pH, a metal chelator such as EDTA in the buffer and minimal headspace all slow it.
Is glutathione a peptide?
Yes. It is a tripeptide of glutamate, cysteine and glycine, with the glutamate joined through its gamma carboxyl. NuVion stocks it in the peptide range as a research material.
What form does glutathione arrive in?
As a lyophilised (freeze-dried) powder in a sealed vial. Bacteriostatic water is sold separately.

Shipping, returns and wholesale orders are covered in the FAQs.

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