The NAD Pathway Pair combines 5-Amino-1MQ with NAD+ for research spanning NNMT enzyme activity and downstream NAD pathway endpoints in metabolic cell models. Both compounds are commonly run together where the question is how methylation load and cofactor availability interact.
- 5-Amino-1MQ 10mg vial, a small molecule inhibitor of the enzyme NNMT
- NAD+ 500mg vial, the coenzyme nicotinamide adenine dinucleotide
NAD Pathway Pair research applications
- LC-MS/MS quantification of NAD+, NADH, nicotinamide, 1-MNA, SAM and SAH in NNMT-expressing cell lines
- Recombinant NNMT assays for IC50 determination, with NAD+ as the calibration and retention time reference for coenzyme quantification
- Sirtuin deacylase activity assays with fluorogenic substrates, read alongside nicotinamide product inhibition
Research profiles: 5-Amino-1MQ and NAD+
What is tested in this pair
This pair contains two products, each supplied in its own vial and each tested on its own. The table lists the published result for every component.
| Component | Purity | Laboratory | Analysed | Certificate |
|---|---|---|---|---|
| 5-Amino-1MQ | 99.41% | Janoshik Analytical | 11 Nov 2025 | View |
| NAD+ | 99.84% | Janoshik Analytical | 17 Oct 2025 | View |
