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NuVion HCG research vial

HCG

Price range: A$49.00 through A$89.00

HCG, human chorionic gonadotropin, studied in LH/CG receptor and gonadal research.

Research use only. Not for human or veterinary use.

All prices are in AUD. Ships from Australia with tracked express shipping, $15 flat, 1 to 2 business days, free on orders over $200. Research use only, not for human or veterinary use.

  • Testing status on this page
  • Same-day dispatch before 2pm
  • Dispatched from Australia
  • Card, Apple Pay & Google Pay

Research use only

Not for human or veterinary use.

Laboratory chemical

Supplied for in vitro research. We publish specifications and handling guidance only, with no protocols and no advice on use.

Not on the ARTG

Absent from the Australian Register of Therapeutic Goods and never evaluated by the TGA for safety, quality or efficacy. Absence from the register is not an approval and does not authorise any other use.

Who can order

You must be 18 or over and purchasing solely for lawful research.

What is HCG?

HCG, human chorionic gonadotropin, is a heterodimeric glycoprotein hormone and the reference ligand at the LH/CG receptor. It is used in Leydig and granulosa cell culture to study cAMP accumulation and steroidogenesis, and NuVion stocks it in Australia in 1,000 IU and 5,000 IU vials.

  • Heterodimeric glycoprotein hormone, ligand at the LH/CG receptor (LHCGR)
  • Alpha and beta subunits totalling 237 amino acids
  • Used in Leydig and granulosa cell culture models
  • Applied in cAMP accumulation and steroidogenesis assays

HCG structure and research use

HCG is built from two subunits. The alpha subunit is shared with LH, FSH and TSH, and the beta subunit gives HCG its receptor specificity. It binds the LH/CG receptor, a G protein-coupled receptor that signals through cyclic AMP. Because it is a glycoprotein, far larger than a short synthetic peptide, its quantity is expressed in International Units.

HCG research applications

  • Cyclic AMP accumulation by HTRF or AlphaScreen in LHCGR-expressing cell lines, as the Gs reference agonist
  • Steroid output in conditioned medium from Leydig or granulosa cell culture, quantified by ELISA or LC-MS
  • Glycoform characterisation of the heterodimer by isoelectric focusing, lectin blot and intact mass analysis
  • Subunit dissociation followed by native gel or size exclusion chromatography under varied pH conditions

HCG key facts

Type Heterodimeric glycoprotein hormone
Subunits Alpha (92 residues) and beta (145 residues)
Total amino acid count 237
Molecular weight Approximately 36 kDa including glycans
Carbohydrate content Around 30 per cent by mass
Receptor LHCGR, a class A G protein-coupled receptor
CAS number 9002-61-3

Research profile: HCG: structure, mechanism and research use

Independent test: a 1,000 IU vial of this product was analysed by Janoshik Analytical on 23 September 2026 and measured 964 IU, test number 234334. HCG is a glycoprotein hormone, so its strength is reported in International Units rather than as a peptide purity percentage. The full report opens from the lab band on this page.

Why buy HCG from NuVion

Testing status on every page

Published results show the measured purity, the date and the certificate.

Australian stock, domestic post

Held in Australia and sent tracked in plain outer packaging.

Specifications

Storing and handling HCG

Before reconstitution
Keep the sealed vial cool, dry and out of direct light. General practice for lyophilised peptides.
After reconstitution
Reconstitute with bacteriostatic or sterile water, store at 2 to 8°C and avoid repeated freeze-thaw cycles. No stability-tested shelf life is published for this product.

Reconstitution and storage Volumes, concentrations and storage at a glance.

HCG questions

Where can I buy HCG in Australia?
NuVion stocks HCG in Australia in 1,000 IU and 5,000 IU vials. Choose a size at the top of this page and check out, and the order is posted from Australian stock on a tracked express service. This product is supplied as a research material only and is not on the Australian Register of Therapeutic Goods.
How much does HCG cost in Australia?
It depends on the vial size. Current prices for the 1,000 IU and 5,000 IU vials are shown at the top of this page in AUD.
What is HCG used for in research?
It is the standard reference agonist at LHCGR, used in cyclic AMP accumulation assays, in competition binding to determine affinity for test compounds, in steroidogenesis assays on Leydig and granulosa cell culture, and in receptor internalisation and arrestin recruitment work.
How does HCG work at the cell level?
HCG binds the extracellular leucine-rich repeat domain of LHCGR with high affinity, in the picomolar range, which makes it the standard reference ligand for that receptor. Binding rotates the hinge region and activates the seven-transmembrane core, coupling principally to Gs. The HCG research profile covers the mechanism in full.
How are the two HCG subunits held together?
The two subunits are held together non-covalently. Both adopt the cystine knot fold, with five disulfide bonds in alpha and six in beta, and the seatbelt loop of the beta subunit latches over the alpha subunit. Free subunits are inactive at the receptor.
How does HCG differ from luteinising hormone?
The difference lies in the beta subunit. Both hormones share the same 92-residue alpha subunit, while the 145-residue beta subunit of HCG differs from that of luteinising hormone chiefly by a 24-residue C-terminal extension carrying four O-linked glycans.
Why does HCG show several bands on isoelectric focusing?
HCG is a mixture of glycoforms, so isoelectric focusing typically shows a ladder of bands. Glycan structures vary with the expression system, which changes charge and apparent mass on gel. That heterogeneity is normal for the molecule.
Why is HCG measured in IU?
HCG is a glycoprotein hormone whose strength is defined by biological activity, which is reported in International Units. The vial label states the IU content.
What form does HCG arrive in?
As a lyophilised (freeze-dried) powder in a sealed vial. Bacteriostatic water is sold separately.

Shipping, returns and wholesale orders are covered in the FAQs.

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